Denamarin is a liver supplement for dogs or cats containing two important liver-protecting ingredients, S-Adenosylmethionine (SAMe) and silybin.
SAMe markedly increases liver glutathione levels which is a potent antioxidant. SAMe also helps protect liver cells from cell death and may help cell repair and regeneration.
Denamarin also has Silybin, which is the most active part of an extract from Milk Thistle known as silymarin. Milk Thistle is a well established herbal liver tonic.
Silybin/silymarin has been shown to support liver function by supporting oxidative balance.
Silybin also stimulates the flow of bile through the liver to aid in the digestion and absorption of nutrients from your pet’s diet.
Silybin also helps with liver cell regeneration and may enhance levels of glutathione.

Manufactured in three strengths for different sizes of dog, Denamarin provides an excellent means of keeping your pet’s liver healthy. Individual dogs from specific breeds such as Doberman Pinschers, Cocker Spaniels, Standard Poodles and some terrier breeds (Bedlingtons, Skyes, Westies) are genetically susceptible to serious liver conditions and Denamarin may provide some useful protection for such dogs.

Dose guide:

Denamarin 90mg for Cats and Small Dogs
Weight – up to 5.5kg: one tablet daily

Denamarin 225mg for Medium Dogs
Weight – 6 to 15.5kg: one tablet daily

Denamarin 425mg for Large Dogs
Weight – 16 to 29.5kg: one tablet daily
Weight – 30 to 54.5kg: two tablets daily
Weight – over 54.5: three tablet daily

The number of tablets can be gradually reduced or increased at any time depending on the pet's needs. Many pets are maintained long-term on every-other-day or every-third-day administration. For optimal absorption, the tablets should be given on an empty stomach, at least one hour before feeding, as the presence of food decreases the absorption of S-Adenosylmethionine.